Business Developer
We are happy to welcome Peter Olofsson-Sahl to the Iscaff team! Peter has extensive experience both as researcher and entrepreneur, and from management of large development projects. From May [...]
16. Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development
Here, we show for the first time that patient-derived xenografts may be used to generate scaffolds enabling analysis of rare tumor types, such as myxoid liposarcoma. We characterized the [...]
15. Proteomics of cell-free breast cancer scaffolds identify clinically relevant imprinted proteins and cancer-progressing properties
In this top publication in a prestigious high impact journal, the composition and presence of imprinted proteins in the breast cancer microenvironment and its potential associations with clinical [...]
13. Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features
In this important publication, PDSs from 78 breast cancer samples with known patient outcomes, were prepared and repopulated with donor breast cancer cell lines, followed by treatment with [...]
12. Interleukin-6 Induces Stem Cell Propagation through Liaison with the Sortilin-Progranulin Axis in Breast Cancer
In this article, a novel cancer stem cell activating mechanism was described, mediated by progranulin and IL-6 secretion through activation of the receptor sortilin. Significant correlations were [...]
