Publication

In a collaborative effort led by Esha Madan and Rajan Gogna from Virginia Commonwealth University School of Medicine in USA,  a novel cancer therapy approach and target has been identified [...]

Here, we show for the first time that patient-derived xenografts may be used to generate scaffolds enabling analysis of rare tumor types, such as myxoid liposarcoma. We characterized the [...]

In this top publication in a prestigious high impact journal, the composition and presence of imprinted proteins in the breast cancer microenvironment and its potential associations with clinical [...]

Publication illustrating that the human cancer microenvironment influences chemotherapy responses. The differences in treatment responses defined by scaffold-cultures shows the prognostic and [...]

In this important publication, PDSs from 78 breast cancer samples with known patient outcomes, were prepared and repopulated with donor breast cancer cell lines, followed by treatment with [...]

In this article, a novel cancer stem cell activating mechanism was described, mediated by progranulin and IL-6 secretion through activation of the receptor sortilin. Significant correlations were [...]

Publication showing that cells cultured on patient-derived scaffolds closely resembled cells cultured on 3D printed scaffolds, contrasting 2D and Matrigel-cultured cells, regardless of a normoxic [...]

New publication showing how individual patient specific microenvironments influence the chemotherapy response in colorectal cancer. [...]

Published patent application for the use of patient derived scaffolds within immune-oncology The patent application covers the use of cell-free scaffolds  as a predictive tool in assessing cancer [...]

Breast Cancer Patient-Derived Scaffolds Can Expose Unique Individual Cancer Progressing Properties of the Cancer Microenvironment Associated with Clinical Characteristics [...]